He is the creator and director of the 2013 Fusion TV docu-series Back Home, his Amazon Studios talk show Pan y Circo, which premiered in 2020, and the 2021 Netflix scripted series Everything Will Be Fine. A separated couple live together for their childs sake in this satirical dramedy about what it means to be a good parent and spouse in todays world.

Season 1 Trailer: Everything Will Be Fine. Since 2010, he has directed three feature films: Abel, Cesar Chavez, and Mr. Created and directed by Mexican TV and film star Diego Luna. Throughout his career, he has appeared in Mexican theater productions and produced a number of film and television projects, many with his close collaborator Gael García Bernal. Produced and directed by the Y Tu Mama Tambien and. From 2018 to 2020, he starred as the drug trafficker Miguel Ángel Félix Gallardo in Narcos: Mexico. Diego Luna is headed to Netflix this August for his latest directorial project, Everything Will Be Fine. Watch Everything Will Be Fine with a subscription on Netflix. In the 2010s, he co-starred in a variety of films like the sci-fi Elysium, comedy Casa de mi Padre, and the animated musical The Book of Life, before starring as Andor in 2016's Rogue One, a role he reprises in the 2022 Disney+ series of the same name.

During the 2000s, he appeared in both Mexican and American films including Frida, Open Range, Dirty Dancing: Havana Nights, The Terminal, Criminal, Milk, Sólo quiero caminar, and Rudo y Cursi. A separated couple live together for their childs sake in this satirical dramedy about what it means to be a good parent and spouse in todays world. Following an early career in Mexican telenovelas, he had his breakthrough in the critically acclaimed 2001 film Y tu mamá también.

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